BIOLOGY 1111
CHAPTER 10
MEIOSIS

ASEXUAL REPRODUCTION

one parent alone passes on a duplicate of all its genes to each new individual

genes- specific sections of a chromosome (DNA)

produces clones

genetically identical copies of the parent

ex: orchids, flatworms, aphids

SEXUAL REPRODUCTION

both parents (each with pairs of genes) pass on one of each gene to their offspring

thus the first cell of a new individual also ends up with pairs of genes

pairs of genes may not be identical

molecular structure of genes change (mutation)

ALLELES

pairs of genes determine individual traits

each molecular form of the same gene is called an allele

one or both alleles determine the traits or characteristics of an individual

ex: 1 allele may code for blonde and another for red hair

VARIATION

all members of sexually reproducing species do not “look” alike

through sexual reproduction, offspring end up with new combinations of alleles, and these lead to variations in their physical and behavioral traits

the resulting variation among offspring may be acted on by agents of natural selection

GAMETES

meiosis divides the chromosomes in a nucleus twice before cell division
variation in traits is a foundation for evolutionary change

meiosis is the first step leading to gamete formation

gametes- sex cells

ex: sperm, ova, egg, pollen

gametes arise from germ cells found in reproductive organs

germ cells have the same chromosome number as the rest of the body cells

the normal number of chromosomes [diploid (2N)] in which their are two of each type of chromosome

if two chromosomes have the same length, shape,  genes dealing with the same traits and they line up with each other at meiosis they are homologous

HOMOLOGOUS CHROMOSOMES

humans ------ 23+23 in germ cells

after meiosis gametes end up with half the number of chromosomes [haploid (N)]

human sperm and egg each have only 23 chromosomes (one of each type)

meiosis reduces the parental chromosome number by half to the haploid number

KEY EVENTS OF MEIOSIS

two key events of meiosis which contribute to new combinations of alleles and thus variations in traits are:

1) crossing over

2) chromosome alignment 

CROSSING OVER

 occurs in the first stages of meiosis as chromosomes begin to condense

corresponding segments of homologous chromosomes are exchanged

genes for the same characteristics have slightly different forms (alleles)

each crossover is a chance to swap different alleles

crossing over leads to genetic recombinations which in turn lead to variation

            CHROMOSOME ALIGNMENT

major shuffling of the entire chromosome

alignment of homologous chromosome at the equator is random

human cell contains 23 chromosomes inherited from the mother (maternal) and23 chromosomes inherited from the father (paternal)

3 chromosome results in 8 possible combinations 23 = 8

random migration of maternal and paternal chromosomes to opposite poles insures a unique gene combination possibility for each gamete

humans have 23 pairs of chromosomes

223 = 8,388,608 possible combinations

MAGNITUDE OF POSSIBILITIES

magnitude of possible chromosome combinations in the formation of gametes and the gene shuffling occuring during crossing- over gives rise to an unlimited number of possible gene make-ups for gametes

GAMETE FORMATION

1) spermatogenesis

formation of male gametes

2) oogenesis

formation of female gametes

SPERMATOGENESIS

1) diploid germ cell enlarges as an immature primary spermatocyte

2) primary spermatocyte undergoes meiosis and divides into 4 haploid daughter cells called spermatids

3) spermatids mature into a flagellated, motile sperm cells

OOGENESIS

1) diploid germ cell develops into immature oocyte

2) oocyte undergoes meiosis and divides into 4 unequally sized cells

cytoplasm is conserved in one single egg

3 remaining non-viable cells are called polar bodies

polar bodies have the correct number of chromosomes but lack enough nutrients and metabolic machinery to be successfully fertilized

FERTILIZATION

the parental chromosome number is restored at fertilization

nuclei of the two haploid gametes fuse

meiosis preceeding the union insures a correct number of chromosomes in each new generation

fertilization contributes to variation in offspring

ex: humans

1) 2-3 crossovers for each chromosome

2) random positioning of pairs of parental chomosomes results in 223 = 8,338,608 possibilities

3) possible number of male and female gametes that are produced and the resulting chance that any two will actually fuse is staggering 

MEIOSIS AND MITOSIS COMPARED

Mitosis

1) single celled organisms use mitosis in asexual reproduction

2) multicellular oganisms use mitosis during growth and tissue repair

Meiosis

1) basis of gamete formation and sexual reproduction

promotes variations in traits among offspring

END

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